United States securities and exchange commission logo November 1, 2022 Neil Desai President and Chief Executive Officer Aadi Bioscience, Inc. 17383 Sunset Boulevard, Suite A250 Pacific Palisades, CA 90272 Re: Aadi Bioscience, Inc. Registration Statement on Form S-3 Filed October 26, 2022 File No. 333-268021 Dear Neil Desai: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Jason Drory at 202-551-8342 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: David Sharon