United States securities and exchange commission logo September 29, 2021 Neil Desai Chief Executive Officer Aadi Bioscience, Inc. 17383 Sunset Boulevard, Suite A250 Pacific Palisades, California 90272 Re: Aadi Bioscience, Inc. Registration Statement on Form S-3 Filed September 24, 2021 File No. 333-259785 Dear Dr. Desai: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Jane Park at 202-551-7439 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Dan Koeppen, Esq.